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Biotinylated Human GFR alpha-like Protein, His,Avitag[TM]

Product Sizes
20 ug
£330.00
GFA-H82E3-20UG
200 ug
£1137.00
GFA-H82E3-200UG
About this Product
SKU:
GFA-H82E3
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor A Alpha-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Immunogen:
GFR alpha-like
Molecular Weight:
41.4 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human GFR alpha-like Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human GDF-15, Fc Tag (Cat. No. GD5-H5269) at 5 ug/mL (100 uL/well) can bind Biotinylated Human GFR alpha-like Protein, His,Avitag (Cat. No. GFA-H82E3) with a linear range of 0.5-16 ng/mL (QC tested).