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Proteins and Peptides

Cynomolgus GFR alpha-like Protein, His Tag

Product Sizes
100 ug
£413.00
GFA-C52H6-100UG
1 mg
£2703.00
GFA-C52H6-1MG
About this Product
SKU:
GFA-C52H6
Additional Names:
GFR alpha like|GFR alpha-like|GFRAL|GRAL
Buffer:
PBS
Extra Details:
GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor A Alpha-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.
Immunogen:
GFR alpha-like
Molecular Weight:
39.6 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins