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Proteins and Peptides

Human GCGR / Glucagon receptor Full Length Protein (VLP)

Product Sizes
20 ug
£1237.00
GCR-H52P5-20UG
100 ug
£1867.00
GCR-H52P5-100UG
500 ug
£5046.00
GCR-H52P5-500UG
About this Product
SKU:
GCR-H52P5
Buffer:
PBS, Arginine, pH7.4
Extra Details:
The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.
Immunogen:
GCGR
Molecular Weight:
91.0 kDa | 56.1 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Immobilized Human GCGR Full Length Protein (VLP) (Cat. No. GCR-H52P5) at 5 ug/mL (100 uL/well) can bind Monoclonal Anti-Human GCGR antibody, Human IgG4 (Crotedumab) with a linear range of 0.1-20 ng/mL (QC tested).
Immobilized Human GCGR Full Length Protein (VLP) (Cat. No. GCR-H52P5) at 5 ug/mL (100 uL/well) can bind Monoclonal Anti-Human GCGR antibody, Human IgG2 (Volagidemab) with a linear range of 0.1-20 ng/mL (Routinely tested).