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Proteins and Peptides

Human Frizzled-7 / FZD7 Protein, Fc Tag

Product Sizes
100 ug
£307.00
FZ7-H5258-100UG
1 mg
£2108.00
FZ7-H5258-1MG
About this Product
SKU:
FZ7-H5258
Additional Names:
Frizzled-7|Fz-7|FZD7|FzE3|hFz7
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.
Immunogen:
Frizzled-7
Molecular Weight:
43.3 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Frizzled-7, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Frizzled-7, Fc Tag (Cat. No. FZ7-H5258) at 1 ug/mL (100 uL/well) can bind Wnt surrogate Human IgG1(D239E,L241M) | Human Lambda with a linear range of 0.1-8 ng/mL (QC tested).