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Proteins and Peptides

Human Frizzled-5 / FZD5 Protein, Fc Tag

Product Sizes
100 ug
£277.00
FZ5-H5259-100UG
1 mg
£1761.00
FZ5-H5259-1MG
About this Product
SKU:
FZ5-H5259
Additional Names:
C2orf31|Frizzled-5|Fz-5|FZD5|FzE5|hFz5
Buffer:
PBS
Extra Details:
Frizzled-5 (FZD5) is also known as FzE5, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta-catenin pathway. FZD5 interacts with GOPC.
Immunogen:
Frizzled-5
Molecular Weight:
42.6 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human Frizzled-5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human Frizzled-5, Fc Tag (Cat. No. FZ5-H5259) at 1 ug/mL (100 uL/well) can bind Wnt surrogate Human IgG1(D239E,L241M) | Human Lambda with a linear range of 0.1-8 ng/mL (QC tested).