Human Frizzled-2 / FZD2 Protein, Fc Tag
Product Sizes
100 ug
£307.00
FZ2-H5251-100UG
1 mg
£2108.00
FZ2-H5251-1MG
About this Product
- SKU:
- FZ2-H5251
- Additional Names:
- Frizzled-2|Fz-2|FZD2|FzE2|hFz2
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Extra Details:
- Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.
- Immunogen:
- Frizzled-2
- Molecular Weight:
- 41.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
