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Proteins and Peptides

Human FUS Protein, MBP,His Tag

Product Sizes
100 ug
£377.00
FUS-H5144-100UG
1 mg
£2461.00
FUS-H5144-1MG
About this Product
SKU:
FUS-H5144
Buffer:
PBS
Extra Details:
FUS (RNA-binding protein FUS) is a DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. It binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. It binds also its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. FUS plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair. In neuronal cells, FUS plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis.
Immunogen:
FUS
Molecular Weight:
97.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human FUS Protein, MBP,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 85%.
Immobilized Human FUS Protein, MBP,His Tag (Cat. No. FUS-H5144) at 1 ug/mL (100 uL/well) can bind FUS antibody, Mouse IgG with a linear range of 0.2-4 ng/mL (QC tested).