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Proteins and Peptides

Human FGF R3 (IIIc) / FGF R3C / CD333 Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£377.00
FGC-H5256-100UG
1 mg
£2703.00
FGC-H5256-1MG
About this Product
SKU:
FGC-H5256
Additional Names:
CD333|FGF R3 (IIIc)|FGF R3C
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Fibroblast growth factor receptors (FGFR) are transmembrane kinase proteins with growing importance in cancer biology given the frequency of molecular alterations and vast interface with multiple other signaling pathways. The FGFR3 gene is at the human chromosomal locus 4p16.3 also encodes two isoforms: FGF R3 (IIIb) FGF R3 (IIIc). Upregulated expression of FGFR3 protein is also found in a significant number of tumors. Additionally, FGFR3 has been found to trigger resistance to tamoxifen via the activation of the PLCG Gamma signaling cascade.
Immunogen:
FGF R3 (IIIc)
Molecular Weight:
64.6 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Human FGF R3 (IIIc), Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 5 ug/mL (100 uL/well) can bind Human FGF R3 (IIIc), Fc Tag (Cat. No. FGC-H5256) with a linear range of 1-39 ng/mL (QC tested).
Immobilized Biotinylated Human FGF basic, Avitag,His Tag (Cat. No. FGC-H81E3) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Human FGF R3 (IIIc), Fc Tag (Cat. No. FGC-H5256) with a linear range of 2-39 ng/mL (Routinely tested).