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Proteins and Peptides

Human FGF-23 (R179Q) Protein, His Tag

Product Sizes
100 ug
£424.00
FG3-H52H3-100UG
1 mg
£3274.00
FG3-H52H3-1MG
About this Product
SKU:
FG3-H52H3
Additional Names:
ADHR|FGF-23|FGF23|HPDR2|HYPF
Buffer:
20 mM MOPS, 150 mM NaCl, pH7.4
Extra Details:
Fibroblast growth factor 23 (FGF23) is is an endocrine member of the family of FGFs and mainly produced in the bone and, upon secretion, forms a complex with a FGF receptor and coreceptor A AlphaKlotho. FGF23 can exert several endocrine functions, such as acting as a hormone on the kidney, stimulating phosphate excretion and suppressing formation of 1,25(OH)2D3, active vitamin D. Moreover, it has paracrine activities on several cell types, including neutrophils and hepatocytes. FGF23 and phosphate have been revealed to be factors relevant in cancer. FGF23 is particularly significant for those forms of cancer primarily affecting bone (e.g., multiple myeloma) or characterized by bone metastasis.
Immunogen:
FGF-23
Molecular Weight:
27.3 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins