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Proteins and Peptides

Cynomolgus Fc epsilon RI alpha Protein, Fc Tag (BLI verified)

Product Sizes
100 ug
£318.00
FCA-C5255-100UG
1 mg
£2314.00
FCA-C5255-1MG
About this Product
SKU:
FCA-C5255
Additional Names:
FCE1A|FCER1A|FcERI
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
High affinity immunoglobulin epsilon receptor subunit alpha (FCER1A) is also known as Fc-epsilon RI-alpha (FcERI), IgE Fc receptor subunit alpha, FCE1A. FCER1A contains two Ig-like (immunoglobulin-like) domains. FCER1A binds to the Fc region of immunoglobulins epsilon and is a high affinity receptor. FCER1A is responsible for initiating the allergic response, which binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. FCER1A plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma.
Immunogen:
Fc epsilon RI alpha
Molecular Weight:
46.9 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus Fc epsilon RI alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Cynomolgus Fc epsilon RI alpha, Fc Tag (Cat. No. FCA-C5255) at 5 ug/mL (100 uL/well) can bind Cynomolgus IgE Fc Protein, His Tag (Cat. No. IGE-C52H3) with a linear range of 0.6-20 ng/mL (Routinely tested).