Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)
Product Sizes
50 ug
£254.00
FC4-M52H3-50UG
100 ug
£377.00
FC4-M52H3-100UG
1 mg
£2703.00
FC4-M52H3-1MG
About this Product
- SKU:
- FC4-M52H3
- Additional Names:
- CD16-2|Fc gamma RIV|Fcgr4
- Buffer:
- PBS
- Extra Details:
- FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions
- Immunogen:
- Fc gamma RIV / CD16-2
- Molecular Weight:
- 22.8 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
