APC-CY7-Labeled Monoclonal Anti-Human CD8 Antibody, Mouse IgG1
Product Sizes
200 tests
£583.00
FABM003-05-200TESTS
About this Product
- SKU:
- FABM003-05
- Application:
- Flow Cytometry
- Buffer:
- PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA
- Clonality:
- Monoclonal
- Conjugate:
- APC-Cyanine 7
- Extra Details:
- CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
- Immunogen:
- CD8
- Physical State:
- Liquid
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Protect from light.
- Supplier:
- ACRO Biosystems
- Type:
- Antibody: Monoclonal Antibody
