Human Endoglin / CD105 Protein, His Tag
Product Sizes
50 ug
£412.00
ENN-H52H9-50UG
500 ug
£2,730.00
ENN-H52H9-500UG
About this Product
- SKU:
- ENN-H52H9
- Additional Names:
- CD105|END|Endoglin|ENG
- Buffer:
- PBS, pH7.4
- Extra Details:
- Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factor-B Beta (TGFB Beta) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor B Beta1 egg (Activin-A), bone morphogenetic protein 2 (BMP-2), and bone morphogenetic protein 7 (BMP-7). Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1). Circulating soluble ENG is also elevated in pulmonary arterial hypertension(PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients.
- Molecular Weight:
- 62.6 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins