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Proteins and Peptides

Human ENO1 Protein, His Tag (HPLC verified)

Product Sizes
100 ug
£954.00
EN1-H5143-100UG
1 mg
£3179.00
EN1-H5143-1MG
About this Product
SKU:
EN1-H5143
Buffer:
20 mM Tris, 150 mM NaCl, pH8.0
Extra Details:
Enolase 1 (ENO1), also known as alpha-enolase, is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. It is ubiquitously expressed and accounts for the majority of cytosolic enolase activity. Beyond its metabolic role, ENO1 is a multifunctional "moonlighting" protein: on the cell surface it acts as a plasminogen receptor promoting extracellular matrix degradation and tumor invasion, while a nuclear isoform (MBP-1) binds the c-MYC promoter and regulates transcription. Overexpression of ENO1 has been linked to cancer progression, autoimmune diseases, and neurodegeneration, making it both a biomarker and a potential therapeutic target.
Immunogen:
ENO1
Molecular Weight:
49.1 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes