Human EDNRB Protein, Flag,His Tag (Detergent)
Product Sizes
20 ug
£1419.00
EDB-H52D3-20UG
100 ug
£3674.00
EDB-H52D3-100UG
500 ug
£8319.00
EDB-H52D3-500UG
About this Product
- SKU:
- EDB-H52D3
- Buffer:
- 50 mM HEPES, 150 mM NaCl, DDM, pH7.5, CHS
- Extra Details:
- Endothelin Receptor B (EDNRB) is a type of G protein-coupled Receptor with the N-terminus located outside the cell. It's widespread in the human body. EDNRB binds to ET and transmits information into the cell through the intracellular Ca2+ phospholipid-dependent protein kinase second messenger system, which promotes the rapid release of calcium in the endoplasmic reticulum and sarcoplasmic reticulum, resulting in the rapid increase of intracellular calcium concentration. Endothelin exerts its biological effects through its receptor (ETR). Endothelin and ETR constitute the endothelin axis. Endothelin axis has pro-tumor effects in various tumors including malignant melanoma (MM), including promoting tumor growth, anti-apoptosis, promoting angiogenesis and promoting tumor metastasis.
- Immunogen:
- EDNRB
- Molecular Weight:
- 61.3 kDa
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
