Monoclonal Anti-Duocarmycin Antibody, Rabbit IgG (M1E06)
Product Sizes
100 ug
£324.00
DUN-MY2287-100UG
1 mg
£1955.00
DUN-MY2287-1MG
About this Product
- SKU:
- DUN-MY2287
- Buffer:
- PBS (pH 7.4)
- translate.label.attr.clone:
- M1E06
- Clonality:
- Monoclonal
- Extra Details:
- Duocarmycin, a DNA minor groove-binding alkylating agent, acts as a payload in antibody-drug conjugates (ADCs) by selectively targeting AT-rich regions of DNA. It forms covalent bonds with the N3 position of adenine, inducing strand breaks and apoptosis through S-phase cell cycle arrest . This mechanism bypasses multidrug resistance pathways, making it potent against aggressive tumors.
- Immunogen:
- Duocarmycin
- Physical State:
- Powder
- Reactivities:
- Rabbit
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Antibody: Monoclonal Antibody
