Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Cynomolgus Complement C1s Protein, His Tag (MALS verified)

Product Sizes
100 ug
£407.00
COS-C52H3-100UG
1 mg
£2585.00
COS-C52H3-1MG
About this Product
SKU:
COS-C52H3
Buffer:
20 mM Tris, 150 mM NaCl, pH7.5
Extra Details:
Complement C1s is a serine protease and a key component of the C1 complex in the classical complement pathway. One C1q molecule binds to a tetramer composed of two C1r and two C1s proteases to form the intact C1 complex. C1s circulates as a zymogen until activated by proteolytic cleavage from activated C1r. Its essential function is to cleave complement components C4 and C2, thereby initiating the formation of the C3 convertase (C4b2a). This step is critical for triggering downstream immune effector functions, including opsonization, inflammation, and membrane attack complex formation.
Immunogen:
Complement C1s
Molecular Weight:
76.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Cynomolgus Complement C1s Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Claseprubart at 5 ug/mL (100 uL/well) can bind Cynomolgus Complement C1s Protein, His Tag (Cat. No. COS-C52H3) with a linear range of 0.01-0.156 ug/mL (QC tested).