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Biotinylated Human Complement C3a Protein, His,Avitag[TM]

Product Sizes
25 ug
£377.00
COA-H82Q3-25UG
200 ug
£1466.00
COA-H82Q3-200UG
About this Product
SKU:
COA-H82Q3
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Immunogen:
Complement C3a
Molecular Weight:
12.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein