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Proteins and Peptides

Cynomolgus Complement C3 Protein, His Tag (MALS verified)

Product Sizes
100 ug
£377.00
CO3-C52H5-100UG
1 mg
£2703.00
CO3-C52H5-1MG
About this Product
SKU:
CO3-C52H5
Additional Names:
Complement C3|CPAMD1
Buffer:
PBS
Extra Details:
C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Immunogen:
Complement C3
Molecular Weight:
71.3 kDa (B Beta chain) and 113.0 kDa (A Alpha chain)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus Complement C3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Cynomolgus Complement C3, His Tag (Cat. No. CO3-C52H5) at 1 ug/mL (100 uL/well) can bind Human Anti-C3,Human IgG1 Human Kappa with a linear range of 0.2-8 ng/mL (QC tested).