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Proteins and Peptides

HCMV (strain Merlin) Glycoprotein B (gB), His Tag (MALS verified)

Product Sizes
50 ug
£377.00
CMB-V52H5-50UG
500 ug
£1867.00
CMB-V52H5-500UG
About this Product
SKU:
CMB-V52H5
Additional Names:
Envelope glycoprotein B|gB|Glycoprotein B
Buffer:
PBS, 0.2 M Arginine, pH7.4
Extra Details:
Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. CMV Virus Envelope Glycoportein B (CMV-GB) can be cleaved into glycoprotein GP55. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. CMV-GB may be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Furthermore, CMV-GB can interact with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also, CMV-GB participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Immunogen:
Glycoprotein B/gB (HCMV)
Molecular Weight:
78.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
HCMV (strain Merlin) Glycoprotein B (gB), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized HCMV (strain Merlin) Glycoprotein B (gB), His Tag (Cat. No. CMB-V52H5) at 1 ug/mL (100 uL/well) can bind Anti-HCMV glycoprotein B antibody-SM5-1, Human IgG1 with a linear range of 0.2-8 ng/mL (QC tested).
Immobilized Anti-HCMV glycoprotein B antibody-SM5-1, Human IgG1 at 1 ug/mL (100 uL/well) can bind HCMV (strain Merlin) Glycoprotein B (gB), His Tag (Cat. No. CMB-V52H5) with a linear range of 1-39 ng/mL (Routinely tested).