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Cynomolgus CLEC4C / BDCA2 Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£371.00
CLC-C5253-100UG
1 mg
£2702.00
CLC-C5253-1MG
About this Product
SKU:
CLC-C5253
Buffer:
PBS
Extra Details:
CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Immunogen:
CLEC4C
Molecular Weight:
45.9 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Lectins
Cynomolgus CLEC4C Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Cynomolgus CLEC4C Protein, Fc Tag (Cat. No. CLC-C5253) at 0.5 ug/mL (100 uL/well) can bind Litifilimab with a linear range of 0.1-2 ng/mL (QC tested).