Human CLEC5A / MDL-1 Protein, His Tag, active dimer (MALS & SPR verified)
Product Sizes
100 ug
£466.00
CLA-H5243-100UG
1 mg
£3274.00
CLA-H5243-1MG
About this Product
- SKU:
- CLA-H5243
- Additional Names:
- C-type lectin domain family 5|CLEC5A|CLECSF5|DAP12-associating lectin 1|MDL-1|MDL1|member A|superfamilymember 5
- Buffer:
- PBS
- Extra Details:
- CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
- Immunogen:
- CLEC5A
- Molecular Weight:
- 39.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
