Human Claudin-9 / CLDN9 Full Length Protein, His,Twin-Strep Tag (Nanodisc)
Product Sizes
20 ug
£2084.00
CL9-H5283-20UG
100 ug
£6123.00
CL9-H5283-100UG
500 ug
£13942.00
CL9-H5283-500UG
About this Product
- SKU:
- CL9-H5283
- Buffer:
- 20 mM HEPES, 150 mM NaCl, pH7.5
- Extra Details:
- Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus; it enables HCV entry into target cells just as efficiently as CLDN1.
- Immunogen:
- Claudin-9
- Molecular Weight:
- 27.9 kda
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
