HEK293/Human APP (GFP) Stable Cell Line
Product Sizes
2 vials
CHEK-ATP081-2VIALS
About this Product
- SKU:
- CHEK-ATP081
- Extra Details:
- Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants: APP695, APP751, and APP770. The majority of APP is cleaved at the plasma membrane by the A Alpha-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with B Beta-secretase cleavage by BACE1 on the N-terminal part of the AB Beta domain, releasing sAPPB Beta from a membrane-anchored fragment named B BetaCTF or C99, which is subsequently cleaved by G Gamma-secretase to release AB Beta.
- Immunogen:
- APP
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- Liquid N2
- Supplier:
- ACRO Biosystems
- Type:
- Cells: Cell Lines