Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag[TM]
Product Sizes
25 ug
£389.00
CDJ-H82F7-25UG
200 ug
£1696.00
CDJ-H82F7-200UG
About this Product
- SKU:
- CDJ-H82F7
- Additional Names:
- CD85|CD85J|ILT2|LILRB1|LIR1|MIR7
- Buffer:
- Tris with Glycine, Arginine and NaCl, pH7.5
- Conjugate:
- Biotin
- Extra Details:
- CD85 antigen-like family member J (CD85J) is also known as Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1 or LIR-1), Immunoglobulin-like transcript 2 (ILT-2), Monocyte/macrophage immunoglobulin-like receptor 7 (MIR7), which belongs to leukocyte immunoglobulin-like receptor (LIR) family. CD85J / LILRB1 Contains 4 Ig-like C2-type (immunoglobulin-like) domains. CD85J / LIR-1 is expressed predominantly on B-cells and monocytes. CD85J is receptor for class I MHC antigens and recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles and is also receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. CD85J / LILRB1 interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. CD85J / LILRB1 inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
- Immunogen:
- LILRB1
- Molecular Weight:
- 75.6 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
