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Proteins and Peptides

Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, Fc Tag&Fc Tag, low endotoxin (MALS verified)

Product Sizes
100 ug
£483.00
CDA-H5253-100UG
1 mg
£31887.00
CDA-H5253-1MG
About this Product
SKU:
CDA-H5253
Buffer:
PBS
Extra Details:
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
Immunogen:
CD8 alpha & beta
Molecular Weight:
44.1 kDa & 43.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human CD8A&CD8B Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human CD8A&CD8B Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDA-H5253) at 5 ug/mL (100 uL/well) can bind Monoclonal Anti-CD8 alpha Antibody, Mouse IgG2a (AM135) with a linear range of 0.03-8 ng/mL (QC tested).
Immobilized Human CD8A&CD8B Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDA-H5253) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-CD8 alpha Antibody, Human IgG1 (AM136) with a linear range of 0.1-63 ng/mL (Routinely tested).