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Proteins and Peptides

Cynomolgus CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)

Product Sizes
100 ug
£436.00
CDA-C52W3-100UG
1 mg
£2809.00
CDA-C52W3-1MG
About this Product
SKU:
CDA-C52W3
Buffer:
PBS
Extra Details:
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.
Immunogen:
CD8 alpha & beta
Molecular Weight:
23.7 kDa & 21.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus CD8A&CD8B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Cynomolgus CD8A&CD8B Heterodimer Protein, His Tag&Tag Free (Cat. No. CDA-C52W3) at 1 ug/mL (100 uL/well) can bind Anti-CD8 alpha Antibody, Human IgG1 with a linear range of 0.06-4 ng/mL (QC tested).