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Proteins and Peptides

Cynomolgus CD39 Protein, His Tag (active enzyme, MALS verified)

Product Sizes
20 ug
£730.00
CD9-C5PH3-20UG
100 ug
£1142.00
CD9-C5PH3-100UG
500 ug
£2909.00
CD9-C5PH3-500UG
About this Product
SKU:
CD9-C5PH3
Buffer:
20 mM Tris, 150 mM NaCl, 20% Glycerol, pH8.0
Extra Details:
CD39 is also known as Ectonucleoside triphosphate diphosphohydrolase 1, ENTPD1, NTPDase 1, Ecto-ATPDase 1, in the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker, but it is also present on the surface of natural killer cells, T cells, and some endothelial cells.Regulatory T cells(Tregs) mediate immunosuppression through multiple, non-redundant, cell-contact dependent and independent mechanisms, a growing body of evidence suggests an important role for the CD39-CD73-adenosine pathway. CD39 ectonucleotidase is the rate-limiting enzyme of a cascade leading to the generation of suppressive adenosine that alters CD4 and CD8 T cell and natural killer cell antitumor activities.
Immunogen:
CD39
Molecular Weight:
52.3 kda
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Cynomolgus CD39 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Anti-CD39 Antibody, Human IgG1 at 1 ug/mL (100 uL/well) can bind Cynomolgus CD39 Protein, His Tag (Cat. No. CD9-C5PH3) with a linear range of 5-78 ng/mL (QC tested).
Immobilized Cynomolgus CD39 Protein, His Tag (Cat. No. CD9-C5PH3) at 1 ug/mL (100 uL/well) can bind Anti-CD39 Antibody, Human IgG1 with a linear range of 0.03-1 ng/mL (Routinely tested).