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Proteins and Peptides

Human CD38 Protein, Fc Tag (MALS verified)

Product Sizes
50 ug
£307.00
CD8-H5255-50UG
1 mg
£2314.00
CD8-H5255-1MG
About this Product
SKU:
CD8-H5255
Additional Names:
cADPr hydrolase 1|CD38|T10
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Immunogen:
CD38
Molecular Weight:
56.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes