Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Human CD117 / c-kit Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£307.00
CD7-H5255-100UG
1 mg
£2108.00
CD7-H5255-1MG
About this Product
SKU:
CD7-H5255
Additional Names:
c-Kit|CD117|KIT|SCFR
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.
Immunogen:
CD117
Molecular Weight:
81.9 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Human CD117, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized ActiveMax® Human SCF, Tag Free at 2 ug/mL (100 uL/well) can bind Human CD117, Fc Tag (Cat. No. CD7-H5255) with a linear range of 0.4-2 ng/mL (QC tested).
Immobilized Human CD117, Fc Tag (Cat. No. CD7-H5255) at 2 ug/mL (100 uL/well) can bind Mouse SCF, His Tag (Cat. No. SCF-M5228) with a linear range of 0.05-1 ng/mL (Routinely tested).