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Proteins and Peptides

Biotinylated Cynomolgus CD117 / c-kit Protein, His,Avitag[TM] (MALS verified)

Product Sizes
25 ug
£377.00
CD7-C82E4-25UG
200 ug
£1466.00
CD7-C82E4-200UG
About this Product
SKU:
CD7-C82E4
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.
Immunogen:
CD117
Molecular Weight:
59.3 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Biotinylated Cynomolgus CD117 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human SCF, His Tag (Cat. No. SCF-H52H3) at 2 ug/mL (100 uL/well) can bind Biotinylated Cynomolgus CD117 Protein, His,Avitag (Cat. No. CD7-C82E4) with a linear range of 0.02-0.313 ug/mL (QC tested).
Immobilized GMP Human SCF Protein (Cat. No. GMP-SCFH25) at 2 ug/mL (100 uL/well) can bind Biotinylated Cynomolgus CD117 Protein, His,Avitag (Cat. No. CD7-C82E4) with a linear range of 0.078-1.25 ug/mL (Routinely tested).