Human CD46 Protein, His Tag (MALS verified)
Product Sizes
50 ug
£342.00
CD6-H5226-50UG
1 mg
£2461.00
CD6-H5226-1MG
About this Product
- SKU:
- CD6-H5226
- Additional Names:
- AHUS2|CD46|MCP|MIC10|TLX|TRA2.10
- Buffer:
- PBS
- Extra Details:
- Complement regulatory protein CD46 is also known as membrane Cofactor Protein (MCP), is a type I membrane protein and is a regulatory part of the complement system. CD46 is expressed by all cells except erythrocytes. MCP acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue, and also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. In T-cells by binding to CD46, A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype. Defects in CD46 are a cause of susceptibility to hemolytic uremic syndrome atypical type 2 (AHUS2).
- Immunogen:
- CD46
- Molecular Weight:
- 33.6 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
