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Proteins and Peptides

Cynomolgus CD206 / MMR Protein, His Tag (MALS verified)

Product Sizes
100 ug
£389.00
CD6-C52H7-100UG
1 mg
£2838.00
CD6-C52H7-1MG
About this Product
SKU:
CD6-C52H7
Buffer:
PBS
Extra Details:
Mrc1 is a conserved checkpoint mediator protein that transduces the replication stress signal to the downstream effector kinase. Mrc1 and its vertebrate homologue Claspin serve as a mediator for replication stress checkpoint signaling, receiving the signal from Mec1/Rad3/ATR sensor kinase and transmitting it to the effector Rad53/Cds1/Chk1 kinase. The loss of mrc1 checkpoint activity results in the aberrant activation of late/dormant origins in the presence of hydroxyurea. Tumor-associated macrophages (TAMs) expressing the multi-ligand endocytic receptor mannose receptor (CD206/MRC1) contribute to tumor immunosuppression, angiogenesis, metastasis, and relapse.
Immunogen:
CD206
Molecular Weight:
158.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus CD206 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Mannan at 20 ug/mL (100 uL/well) can bind Cynomolgus CD206 Protein, His Tag (Cat. No. CD6-C52H7) with a linear range of 0.039-1.25 ug/mL (QC tested).