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Proteins and Peptides

Human CD74 / DHLAG Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£377.00
CD4-H5256-100UG
1 mg
£2703.00
CD4-H5256-1MG
About this Product
SKU:
CD4-H5256
Additional Names:
CD74|CLIP|DHLAG|HLADG|Ia-GAMMA|II|INVG34|p33
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Cluster of Differentiation 74 (CD74) is also known as HLA class II histocompatibility antigen gamma chain (HLADG), DHLAG, Ia-GAMMA, invariant chain (Abbreviated Ii). CD74 / HLADG is a polypeptide involved in the formation and transport of MHC class II protein. The cell surface form of the invariant chain is known as CD74. CD74 is upregulated in several cancers and is also expressed by non-immune cells during inflammation. CD74 plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha / beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal / lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 / DHLAG also serves as cell surface receptor for the cytokine MIF.
Immunogen:
CD74
Molecular Weight:
47.9 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human CD74, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human Cathepsin L Protein, His Tag (Cat. No. CAL-H52H3) at 5 ug/mL (100 uL/well) can bind Human CD74, Fc Tag (Cat. No. CD4-H5256) with a linear range of 0.005-1.25 ug/mL (Routinely tested).