Biotinylated Human CCR7 Full Length Protein, His,Flag Tag&Avitag[TM] (Detergent)
Product Sizes
20 ug
£1878.00
CC7-H82D4-20UG
100 ug
£4104.00
CC7-H82D4-100UG
About this Product
- SKU:
- CC7-H82D4
- Buffer:
- 50 mM HEPES, 150 mM NaCl, Buffer B, pH7.5
- Conjugate:
- Biotin
- Extra Details:
- The monoclonal antibody mAb-729 reacts with the human CC chemokine receptor, CCR7. The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis.
- Immunogen:
- CCR7
- Molecular Weight:
- 61.2 kDa
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
