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Proteins and Peptides

Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)

Product Sizes
20 ug
£195.00
CC2-H5255-20UG
50 ug
£389.00
CC2-H5255-50UG
1 mg
£3504.00
CC2-H5255-1MG
About this Product
SKU:
CC2-H5255
Additional Names:
C-C motif chemokine 2|CCL2|MCAF|MCP-1
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Immunogen:
CCL2
Molecular Weight:
35.1 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human CCL2, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human CCL2, Fc Tag (Cat. No. CC2-H5255) at 5 ug/mL (100 uL/well) can bind Human CCR2 Full Length Protein, Flag,His Tag (Cat. No. CC2-H52D4) with a linear range of 0.005-0.313 ug/mL (QC tested).
Immobilized Human CCL2, Fc Tag (Cat. No. CC2-H5255) at 5 ug/mL (100 uL/well) can bind Anti-MCP-1 / CCL2 Antibody, Mouse Fc (1B7) with a linear range of 0.2-5 ng/mL (Routinely tested).