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Proteins and Peptides

APC-Labeled Human Carbonic Anhydrase IX / CA9 (38-414) Protein, His Tag (Site-specific conjugation)

Product Sizes
25 tests
£342.00
CA9-HA2H7-25TESTS
200 tests
£2,142.00
CA9-HA2H7-200TESTS
About this Product
SKU:
CA9-HA2H7
Buffer:
PBS, 0.5% BSA, pH7.4
Extra Details:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (A Alpha, B Beta, G Gamma, D Delta and E Epsilon). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.
Molecular Weight:
44.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles. Protect from light.
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes