Cynomolgus Cadherin-11 Protein, His Tag (MALS verified)
Product Sizes
100 ug
£371.00
CA1-C52H3-100UG
1 mg
£2703.00
CA1-C52H3-1MG
About this Product
- SKU:
- CA1-C52H3
- Buffer:
- PBS
- Extra Details:
- Cadherin-11 is a type II cadherin which mediates cell-to-cell homophilic interactions. Cadherin-11 is mainly expressed on mesenchymal cells and is essential for tissue migration and organization during embryogenesis, while its expression on epithelial cancer cells is implicated in tumor progression and metastasis suggesting a potential role in the epithelial-to-mesenchymal transition phenomenon. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. In addition, cadherin-11 has been shown to increase the invasive capacity of Fibroblast-like Synoviocytes (FLS) and consequently be involved in the formation of the rheumatoid pannus.
- Immunogen:
- Cadherin-11
- Molecular Weight:
- 63.8 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
