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Proteins and Peptides

Human FGF basic Protein, premium grade

Product Sizes
20 ug
£127.00
BFF-H4117-20UG
50 ug
£168.00
BFF-H4117-50UG
1 mg
£866.00
BFF-H4117-1MG
About this Product
SKU:
BFF-H4117
Additional Names:
BFGF|FGF basic|FGF2|FGFB|HBGF-2
Buffer:
PBS
Extra Details:
FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF basic has been isolated from a number of sources, including neural tissue, pituitary, adrenal cortex, corpus luteum, and placenta. This factor contains four cysteine residues, but reduced FGF basic retains full biological activity, indicating that disulfide bonds are not required for this activity. bFGF is a critical component of human embryonic stem cell culture medium; the growth factor is necessary for the cells to remain in an undifferentiated state, although the mechanisms by which it does this are poorly defined. It has been demonstrated to induce gremlin expression which in turn is known to inhibit the induction of differentiation by bone morphogenetic proteins. It is necessary in mouse-feeder cell dependent culture systems, as well as in feeder and serum-free culture systems.
Immunogen:
FGF basic
Molecular Weight:
16.5 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human FGF basic, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 5 ug/mL (100 uL/well) can bind Human Glypican 3 Protein, Fc Tag (Cat. No. GP3-H5258) with a linear range of 0.3-5 ng/mL (QC tested).
Immobilized Human FGF basic, premium grade (Cat. No. BFF-H4117) at 5 ug/mL (100 uL/well) can bind Human Glypican 1, Fc Tag (Cat. No. GP1-H5254) with a linear range of 1-20 ng/mL (Routinely tested).