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Proteins and Peptides

Human Bcl-x / BCL2L1 Protein, GST Tag

Product Sizes
100 ug
£265.00
BC1-H513A-100UG
1 mg
£1602.00
BC1-H513A-1MG
About this Product
SKU:
BC1-H513A
Additional Names:
Bcl-X|Bcl-XL|bcl-xS|Bcl2-L-1|BCL2L|BCL2L1|BCLX|BCLXL|BCLXS|S
Buffer:
20 mM Tris, 100 mM NaCl, 10 mM GSH, pH7.5
Extra Details:
Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Immunogen:
Bcl-x
Molecular Weight:
50.6 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins