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Proteins and Peptides

Human BAFFR / TNFRSF13C Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£400.00
BAR-H5253-100UG
1 mg
£2850.00
BAR-H5253-1MG
About this Product
SKU:
BAR-H5253
Buffer:
PBS
Extra Details:
BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
Immunogen:
BAFFR
Molecular Weight:
33.1 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human BAFFR Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human BAFF, His Tag (Cat. No. BAF-H5248) at 5 ug/mL (100 uL/well) can bind Human BAFFR Protein, Fc Tag (Cat. No. BAR-H5253) with a linear range of 0.2-4 ng/mL (QC tested).
Immobilized Human BAFFR Protein, Fc Tag (Cat. No. BAR-H5253) at 1 ug/mL (100 uL/well) can bind Anti-BAFFR Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).