Biotinylated Human B7-H6 / NCR3LG1 Protein, His,Avitag[TM]
Product Sizes
25 ug
£365.00
B76-H82E5-25UG
200 ug
£1,565.00
B76-H82E5-200UG
About this Product
- SKU:
- B76-H82E5
- Additional Names:
- B7 Homolog 6|B7-H6|NCR3LG1
- Buffer:
- PBS, pH7.4
- Extra Details:
- The B7 family of genes is essential in the regulation of the adaptive immune system. one of which is the recently discovered B7H6. Humans and rats have a single B7H6 gene; however, many B7H6 genes were detected in a single large cluster in the Xenopus genome. Chimeric antigen receptor (CAR) T-cell therapies have demonstrated durable and potentially curative therapeutic efficacy against B-cell leukemia in clinical trials. In this study, B7H6, a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
- Molecular Weight:
- 30.4 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein