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Proteins and Peptides

Mouse APP / N-APP Protein, His Tag (MALS verified)

Product Sizes
100 ug
£401.00
APP-M52H3-100UG
500 ug
£1225.00
APP-M52H3-500UG
About this Product
SKU:
APP-M52H3
Additional Names:
ABPP|Amyloid-beta A4 protein|APPI
Buffer:
PBS
Extra Details:
Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the A Alpha-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with B Beta-secretase cleavage by BACE1 on the N-terminal part of the AB Beta domain, releasing sAPPB Beta from a membrane-anchored fragment named B BetaCTF or C102, which is subsequently cleaved by G Gamma-secretase to release AB Beta.
Immunogen:
APP
Molecular Weight:
31.9 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins