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Proteins and Peptides

Human APRIL / TNFSF13 Protein, Fc Tag

Product Sizes
100 ug
£377.00
APL-H5263-100UG
1 mg
£2461.00
APL-H5263-1MG
About this Product
SKU:
APL-H5263
Buffer:
PBS, 0.5 M Arginine, pH7.4
Extra Details:
APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFSF13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.
Immunogen:
APRIL
Molecular Weight:
42.2 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human APRIL Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human BCMA, Mouse IgG2a Fc Tag (Cat. No. BCA-H5253) at 5 ug/mL (100 uL/well) can bind Human APRIL Protein, Fc Tag (Cat. No. APL-H5263) with a linear range of 0.06-2 ng/mL (QC tested).
Immobilized Human APRIL Protein, Fc Tag (Cat. No. APL-H5263) at 2 ug/mL (100 uL/well) can bind Human BCMA, Mouse IgG2a Fc Tag (Cat. No. BCA-H5253) with a linear range of 0.1-1 ng/mL (Routinely tested).