Human Activin RIB / ACVR1B Protein, His Tag
Product Sizes
100 ug
£371.00
ACB-H52H4-100UG
1 mg
£2456.00
ACB-H52H4-1MG
About this Product
- SKU:
- ACB-H52H4
- Additional Names:
- ACTR-IB|ACVR1b|ACVRLK4|ALK4|SKR2
- Buffer:
- PBS
- Extra Details:
- Activin receptor type-1B (ACVR1B) is also known as Activin receptor-like kinase 4 (ALK-4), Serine/threonine-protein kinase receptor R2 (SKR2), which belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. ACVR1B contains one GS domain and one protein kinase domain. The catalytic activity of ACVR1B is "ATP + [receptor-protein] = ADP + [receptor-protein] phosphate". ACVR1B acts as a transducer of activin or activin like ligands (e.g., inhibin) signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. These go on to recruit the R-SMADs SMAD2 or SMAD3. ACVR1B also transduces signals of nodal, GDF-1, and Vg1.
- Immunogen:
- Activin RIB
- Molecular Weight:
- 13.3 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
