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Proteins and Peptides

Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag

Product Sizes
100 ug
£377.00
ACB-H5253-100UG
1 mg
£2461.00
ACB-H5253-1MG
About this Product
SKU:
ACB-H5253
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Immunogen:
Activin RIB & Activin RIIB
Molecular Weight:
37 kDa & 39.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human Activin A Protein, Tag Free (Cat. No. ACA-H421b) at 5 ug/mL (100 uL/well) can bind Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag (Cat. No. ACB-H5253) with a linear range of 0.3-10 ng/mL (QC tested).
Immobilized Human latent GDF-8, His Tag (Cat. No. GD8-H5243) at 5 ug/mL (100 uL/well) can bind Human Activin RIB & Activin RIIB Protein, Fc Tag&Fc Tag (Cat. No. ACB-H5253) with a linear range of 0.005-0.156 ug/mL (Routinely tested).