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Proteins and Peptides

Human / Cynomolgus Activin RIIA / ACVR2A Protein, Fc Tag

Product Sizes
200 ug
£318.00
ACA-H5269-200UG
1 mg
£1219.00
ACA-H5269-1MG
About this Product
SKU:
ACA-H5269
Additional Names:
Activin receptor type IIA|ACTRIIA
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Extra Details:
Activin receptor type-2A (ACVR2A) is also known as Activin receptor type IIA, ACTR-IIA, ACTRIIA and ACVR2,which is single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily,TKL Ser/Thr protein kinase family and TGFB receptor subfamily.On ligand binding,ACVR2A can forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.ACVR2A is Receptor for activin A, activin B and inhibin A as well. Several type I I activin receptors have been identified and bind to different activins with different affinities.
Immunogen:
Activin RIIA
Molecular Weight:
39.9 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
Human / Cynomolgus Activin RIIA Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human Activin A Protein, Tag Free (Cat. No. ACA-H421b) at 5 ug/mL (100 uL/well) can bind Human / Cynomolgus Activin RIIA / ACVR2A Protein, Fc Tag (Cat. No. ACA-H5269) with a linear range of 0.2-8 ng/mL (QC tested).
Immobilized Human / Cynomolgus Activin RIIA Protein, Fc Tag (Cat. No. ACA-H5269) at 1 ug/mL (100 uL/well) can bind Bimagrumab with a linear range of 0.1-3 ng/mL (Routinely tested).