Anti-erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)]
Product Sizes
5 mg
BAB0183-BB-5MG
About this Product
- SKU:
- BAB0183-BB
- Additional Names:
- CD340; Metastatic lymph node gene 19 protein (MLN 19); Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; p185HER2; EGFR
- Application:
- ELISA, Flow Cytometry, Immunohistochemistry
- Buffer:
- PBS
- translate.label.attr.clone:
- 4D5-8 (trastuzumab)
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against human HER2 (Fab) and one arm directed against human CD3e (scFv).
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:bAb0183-BB
