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Antibodies

Anti-EGFRvIII [L8A4]

Product Sizes
50 ug
Was £474.00 £450.00
BAB0164-50UG
About this Product
SKU:
BAB0164
Additional Names:
Epidermal Growth Factor Receptor variant III
Application:
ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Surface Plasmon Resonance, Western Blot
Buffer:
PBS with 0.02% Proclin 300.
translate.label.attr.clone:
L8A4
Clonality:
Recombinant Monoclonal
Extra Details:
This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against human EGFRvIII (Fab) and one arm directed against mouse CD3e (scFv).
Formulation:
PBS with 0.02% Proclin 300.
Host:
Mouse
Immunogen:
Pep 3-KLH (Pep 3 is a 14-amino acid peptide corresponding to the predicted amino acid sequence at the fusion junction and KLH stands for keyhole limpet hemocyanin) at da 40 and 103, HC2 20 d2 cells at day 1, 25, 74, 87. And fusion with the nonimmunoglobulin-secreting Kearney variant of P3X63/Ag8.653.
Isotype:
IgG2a
Purification:
Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Binds EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis.
Storage Conditions:
2-8[o]C Aliquot., -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
Absolute Antibody
Type:
Antibody: Recombinant Antibodies