Anti-EGFRvIII [L8A4]
Product Sizes
5 mg
BAB0164-BB-5MG
About this Product
- SKU:
- BAB0164-BB
- Additional Names:
- Epidermal Growth Factor Receptor variant III
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Surface Plasmon Resonance, Western Blot
- Buffer:
- PBS
- translate.label.attr.clone:
- L8A4
- Clonality:
- Recombinant Monoclonal
- Extra Details:
- This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against human EGFRvIII (Fab) and one arm directed against mouse CD3e (scFv).
- Formulation:
- PBS only.
- Host:
- Mouse
- Immunogen:
- Pep 3-KLH (Pep 3 is a 14-amino acid peptide corresponding to the predicted amino acid sequence at the fusion junction and KLH stands for keyhole limpet hemocyanin) at da 40 and 103, HC2 20 d2 cells at day 1, 25, 74, 87. And fusion with the nonimmunoglobulin-secreting Kearney variant of P3X63/Ag8.653.
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Binds EGFRvIII, a mutated form of EGFR, plays a prominent role in tumorigenesis.
- Storage Conditions:
- 2-8[o]C, -20[o]C aliquoted. Avoid freeze/thaw cycles.
- Supplier:
- Absolute Antibody
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:bAb0164-BB
